Brachyspira Hyodysentiae is a spirochete that affects swine causing among other symptoms colitis with superficial coagulation necrosis, erosion of the epithelium and severe inflammation of the mucosa and submucosa.
Curcumin is a natural polyphenol extracted from turmeric longa that shows a series of very interesting activities to alleviate the symptoms produced by colon inflammations. Several very interesting actions of curcumin have been described, such as an anticoagulant effect by significantly prolonging the thromboplastin and prothrombin time, a broad bactericidal spectrum, and a potent anti-inflammatory effect. In fact, in humans it is used as an anti-inflammatory to alleviate symptoms such as those caused by ulcerative colitis, a disease with some symptoms very similar to swine dysentery.
The mechanisms of curcumin’s anti-inflammatory effect could be due to suppression of nuclear factor kappa enhancer of activated B-cell light chain (NF-κB), suppression of interleukin-1 (IL-1) and tumor necrosis factor alpha (TNF-α), in addition to direct neutralization of free radicals that exist in excess in any inflamed tissue.
In NBG we have developed NBG EnteroShield-BH to try to alleviate the effects of swine dysentery, this product contains among others turmeric enhanced with NBG Protect and NBG Bioboost technology.
For more information about NBG EnteroShield-BH please do not hesitate to contact us:
Finally, here is an article on the effect of curcumin to treat ulcerative colitis. Enjoy the article!