How Mycoplasma infection in broilers causes oxidative stress affecting immune function and structural integrity of tissues

Dear colleagues,

We have recently obtained very interesting results of our natural metabolic antioxidant NBG OxiShield against a challenge by Heat and Mycoplasma in chickens.

NBG OxiShield is a product designed as a powerful antioxidant and recoverer of the endogenous antioxidant system of the organism, its design from a holistic point of view acts on the problem, on the origin of the problem and on the consequences of the problem.

In future publications we will show you these incredible results, but in the meantime I am pleased to show you an article that shows the keys to why our product has worked so efficiently.

In this article we will see how Mycoplasma gallisepticum (MG) induces a dysregulated immune response in the lungs and airways of poultry.

The data revealed that MG infection induced oxidative stress and decreased antioxidant responses in Bursa of Fabricius ( BOF ) tissues compared to the control group.

Histopathological study showed pathological changes including reduced lymphocytes and increased inflammatory cell infiltration in the MG infection group.

Increased cytokine activity was observed in the MG infection group compared to the control group. Meanwhile, the mRNA and protein expression level of apoptosis-related genes were significantly (p < 0.05) increased in the MG infection group.

In addition, the bacterial load was significantly increased in the MG infection group compared with the control group.

These results suggest that MG infection impaired the structural integrity, induced oxidative stress and apoptosis in chicken BOF tissues, which could be the possible causes of impaired immune function in chicken BOF.

So this would explain how in a similar trial with NBG OxiShield we have seen results where both mortality and animal production results improve dramatically when the problem is attacked with a holistic antioxidant that provides both direct and indirect solutions to the problem.

Enjoy the article.

Photography: M.H.B. Catroxo and A.M.C.R.P.F. Martins, CC BY 3.0 <https://creativecommons.org/licenses/by/3.0>, via Wikimedia Commons