How Mycoplasma infection in chickens causes oxidative stress, affecting immune function and tissue structural integrity
Dear colleagues,
We have recently obtained very interesting results from our natural metabolic antioxidant NBG OxiShield when challenged by heat and mycoplasma in chickens.
NBG OxiShield is a product designed as a powerful antioxidant and restorer of the body’s endogenous antioxidant system. From a holistic point of view, it acts on the problem, its origin and its consequences.
In future publications, we will show you these incredible results, but in the meantime, I am pleased to share an article that reveals the keys to why our product has worked so effectively.
In this article, we will look at how Mycoplasma gallisepticum (MG) induces a dysregulated immune response in the lungs and respiratory tract of poultry.
The data revealed that MG infection induced oxidative stress and decreased antioxidant responses in the tissues of the bursa of Fabricius (BOF) compared to the control group.
Histopathological examination revealed pathological changes including a reduction in lymphocytes and increased inflammatory cell infiltration in the MG infection group.
An increase in cytokine activity was observed in the MG infection group compared to the control group. Meanwhile, the expression level of mRNA and proteins of apoptosis-related genes significantly increased (p < 0.05) in the MG infection group.
Furthermore, the bacterial load increased significantly in the MG infection group compared to the control group.
These results suggest that MG infection impaired structural integrity, induced oxidative stress and apoptosis in chicken BOF tissues, which could be the possible causes of impaired immune function in chicken BOF.
This would explain how, in a similar trial with NBG OxiShield, we have seen results in which both mortality and production outcomes in animals improve dramatically when the problem is tackled with a holistic antioxidant that provides direct and indirect solutions to the problem.
Disfruten del artículo.
Photo: M.H.B. Catroxo und A.M.C.R.P.F. Martins, CC BY 3.0 <https://creativecommons.org/licenses/by/3.0>
, über Wikimedia Commons
